TSPAN11

Across TCGA cell cohorts, TSPAN11 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN11-associated genes across cancer lineages are LIM2, CXorf51A, and TAS2R41. Each is linked with TSPAN11 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN11-to-partner and partner-to-TSPAN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIM2 grouped by TSPAN11-low versus TSPAN11-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN11→partner) and Y-score (partner→TSPAN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LIM2 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.055	+4.887	<.001	.009	3	1
LARGE_INTESTINE	TAS2R41 →	+0.035	+3.345	<.001	.007	3	1
LARGE_INTESTINE	PIGY →	+1.857	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

LIM2 by TSPAN11 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →