TSNAX

Across TCGA cell cohorts, TSNAX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,765 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSNAX-associated GO terms across cancer lineages are Nuclear pore organization, Regulation of endoplasmic reticulum tubular network organization, and Establishment of protein localization to endoplasmic reticulum membrane. Each is linked with TSNAX in more than 15 cancer types. Because this analysis shows association rather than direction, both TSNAX-to-partner and partner-to-TSNAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by TSNAX-low versus TSNAX-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSNAX→partner) and Y-score (partner→TSNAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear pore organization →	+0.156	+0.853	<.001	<.001	3	16
PANCREAS	Regulation of endoplasmic reticulum tubular network organization →	+0.101	+0.705	<.001	.004	3	15
KIDNEY	Establishment of protein localization to endoplasmic reticulum membrane →	+0.103	+0.595	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.142	+0.726	.001	<.001	3	15
KIDNEY	Regulation of formation of translation preinitiation complex →	+0.093	+0.523	.005	<.001	3	14
KIDNEY	Negative regulation of formation of translation preinitiation complex →	+0.093	+0.523	.005	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,765 associations by consensus.

Nuclear pore organization by TSNAX expression — BONE

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