TSNARE1

Across TCGA pan-cancer cohorts, TSNARE1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TSNARE1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TSNARE1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TSNARE1 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where TSNARE1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSNARE1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.481	<.001	11	view →
COAD	All	IV	+1.621	<.001	10	view →
LIHC	Male	II,III,IV	+1.085	<.001	9	view →
HNSC	All	All	+0.436	.004	7	view →
STAD	Male	II,III,IV	+0.971	<.001	6	view →
CHOL	All	All	+2.101	<.001	5	view →
BRCA	Female	All	−0.264	.008	4	view →
THCA	All	All	−0.207	.004	3	view →
READ	All	All	+1.165	.001	2	view →
PRAD	All	All	+0.231	.021	2	view →
LUSC	All	All	+0.256	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TSNARE1–KIRC

Open the KIRC breakdown →