TSLP

Across TCGA patient cohorts, TSLP RNA expression is significantly associated with the protein abundance of many other proteins, with 12,096 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TSLP-associated proteins across cancer lineages are SERPINB5, CYGB, and RBM47. Each is linked with TSLP in more than 3 cancer types. Because this analysis shows association rather than direction, both TSLP-to-partner and partner-to-TSLP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSLP versus SERPINB5 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSLP→partner) and Y-score (partner→TSLP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SERPINB5 →	+1.151	+0.691	<.001	<.001	3	4
BRCA	CYGB →	+0.478	+0.339	<.001	.002	3	4
LSCC	RBM47 →	-0.295	-0.563	.001	.003	3	3
BRCA	SEC16A_S1069 →	-0.499	-0.486	<.001	<.001	3	3
LSCC	KRT5_S571 →	+1.302	+0.703	.003	.002	3	3
LSCC	MAP1B →	+0.684	+0.480	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,096 associations by consensus.

TSLP vs SERPINB5 — LSCC

Explore this scatter interactively →