TSLP

Across TCGA cell cohorts, TSLP RNA expression is significantly associated with the RNA expression of many other genes, with 5,296 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSLP-associated genes across cancer lineages are CARD16, TSPAN5, and APOL6. Each is linked with TSLP in more than 4 cancer types. Because this analysis shows association rather than direction, both TSLP-to-partner and partner-to-TSLP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSLP versus CARD16 in CNS, with a Pearson correlation of 0.50.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSLP→partner) and Y-score (partner→TSLP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CARD16 →	+2.669	+1.469	<.001	<.001	3	5
SKIN	TSPAN5 →	+2.040	+1.335	<.001	.002	3	5
BREAST	APOL6 →	+1.744	+0.640	<.001	<.001	2	5
LIVER	STAC →	+2.475	+1.365	.001	.007	2	5
BREAST	CAV2 →	+3.739	+0.642	<.001	<.001	3	4
LIVER	CASP1 →	+2.768	+1.635	.001	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,296 associations by consensus.

TSLP vs CARD16 — CNS

Explore this scatter interactively →