TSKS

Across TCGA cell cohorts, TSKS RNA expression is significantly associated with the go_rna of many other GO terms, with 853 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSKS-associated GO terms across cancer lineages are Positive regulation of sterol transport, Positive regulation of cholesterol transport, and Sodium ion transport. Each is linked with TSKS in more than 5 cancer types. Because this analysis shows association rather than direction, both TSKS-to-partner and partner-to-TSKS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of sterol transport grouped by TSKS-low versus TSKS-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSKS→partner) and Y-score (partner→TSKS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of sterol transport →	+0.095	+0.083	.001	.008	2	6
STOMACH	Positive regulation of cholesterol transport →	+0.095	+0.083	.001	.008	2	6
CNS	Sodium ion transport →	-0.044	-0.037	<.001	.006	2	6
LUNG_NSCLC_LUAD	Sodium ion transmembrane transport →	-0.039	-0.242	.001	.001	3	5
URINARY_TRACT	Positive regulation of protein sumoylation →	+0.092	+0.045	<.001	.003	2	5
CNS	Response to biphenyl →	+0.119	+0.067	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 853 associations by consensus.

Positive regulation of sterol transport by TSKS expression — STOMACH

Explore this box plot interactively →