TSHZ2

Across TCGA patient cohorts, TSHZ2 mutation is significantly associated with the RNA expression of many other genes, with 4,123 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSHZ2-associated genes across cancer lineages are RNU1-62P, MSANTD3, and GSKIP. Each is linked with TSHZ2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TSHZ2-to-partner and partner-to-TSHZ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-62P grouped by TSHZ2-low versus TSHZ2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSHZ2→partner) and Y-score (partner→TSHZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-62P →	+0.231	+3.411	<.001	.005	3	4
UCEC	MSANTD3 →	+0.368	+1.595	.002	<.001	3	4
COAD	GSKIP →	+0.614	+2.807	<.001	.002	3	4
UCEC	EMID1 →	-1.102	-2.159	<.001	.002	3	4
STAD	PKM →	+0.953	+3.203	<.001	.008	3	4
COAD	CDCA2 →	+0.718	+2.183	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,123 associations by consensus.

RNU1-62P by TSHZ2 expression — BLCA

Explore this box plot interactively →