Across TCGA cell cohorts, TSGA13 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSGA13-associated genes across cancer lineages are GHR, KCNK17, and FBXW10. Each is linked with TSGA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSGA13-to-partner and partner-to-TSGA13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSGA13→partner) and Y-score (partner→TSGA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GHR →	+0.545	+3.517	<.001	.003	3	1
LARGE_INTESTINE	KCNK17 →	+0.071	+3.906	<.001	.002	3	1
LARGE_INTESTINE	FBXW10 →	+0.231	+3.491	<.001	.004	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	PTX4 →	+0.125	+3.743	<.001	.001	3	1
LARGE_INTESTINE	SPI1 →	+0.140	+3.169	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

TSGA13 survival (RNA) · tumor vs normal (RNA) · all TSGA13 data types