Across TCGA patient cohorts, TSC22D2 mutation is significantly associated with the RNA expression of many other genes, with 4,582 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSC22D2-associated genes across cancer lineages are MIR4798, RNU1-139P, and RNU6-987P. Each is linked with TSC22D2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSC22D2-to-partner and partner-to-TSC22D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D2→partner) and Y-score (partner→TSC22D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR4798 →	+0.534	+4.712	.003	.007	3	3
HNSC	RNU1-139P →	+0.239	+7.954	<.001	.008	3	2
BLCA	RNU6-987P →	+0.418	+4.914	<.001	<.001	3	2
SKCM	MIR4288 →	+0.267	+4.328	<.001	.007	3	2
SKCM	HMGN1P31 →	+0.066	+4.797	<.001	.003	3	2
BRCA	MIR2392 →	+0.344	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,582 associations by consensus.

Exploration

TSC22D2 survival (RNA) · tumor vs normal (RNA) · all TSC22D2 data types