TSC22D1

Across TCGA patient cohorts, TSC22D1 protein abundance is significantly associated with the RNA expression of many other genes, with 22,486 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TSC22D1-associated genes across cancer lineages are NEK3, COG3, and KANK2. Each is linked with TSC22D1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TSC22D1-to-partner and partner-to-TSC22D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSC22D1 versus NEK3 in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D1→partner) and Y-score (partner→TSC22D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEK3 →	+0.628	+0.423	<.001	<.001	3	7
OV	COG3 →	+0.578	+0.634	<.001	.001	3	7
BRCA	KANK2 →	+0.753	+0.270	<.001	.002	3	7
OV	GPALPP1 →	+0.688	+0.781	<.001	<.001	3	7
COAD	CAB39L →	+0.965	+0.348	<.001	<.001	3	6
UCEC	GLT8D2 →	+0.808	+0.383	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,486 associations by consensus.

TSC22D1 vs NEK3 — GBM

Explore this scatter interactively →