TSC22D1

Across TCGA cell cohorts, TSC22D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,661 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSC22D1-associated GO terms across cancer lineages are Negative regulation of stem cell proliferation, Regulation of miRNA metabolic process, and Regulation of protein localization to membrane. Each is linked with TSC22D1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TSC22D1-to-partner and partner-to-TSC22D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stem cell proliferation grouped by TSC22D1-low versus TSC22D1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D1→partner) and Y-score (partner→TSC22D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of stem cell proliferation →	+0.998	+1.382	<.001	<.001	3	13
OVARY	Regulation of miRNA metabolic process →	+0.062	+0.975	.002	.002	3	10
STOMACH	Regulation of protein localization to membrane →	+0.060	+0.908	.001	.004	3	9
CNS	Regulation of epithelial to mesenchymal transition →	+0.069	+0.940	<.001	<.001	3	8
STOMACH	Positive regulation of protein localization to plasma membrane →	+0.085	+1.091	.001	<.001	3	8
LUNG_SCLC	Negative regulation of hematopoietic stem cell differentiation →	+0.128	+0.828	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,661 associations by consensus.

Negative regulation of stem cell proliferation by TSC22D1 expression — BLOOD_Lymphoma

Explore this box plot interactively →