TSC22D1-AS1

Across TCGA pan-cancer cohorts, TSC22D1-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TSC22D1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TSC22D1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TSC22D1-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and COAD are the cancer types where TSC22D1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSC22D1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.364	<.001	10	view →
KICH	All	All	−0.559	<.001	8	view →
COAD	Male	II,III,IV	+0.510	<.001	6	view →
LIHC	All	All	+0.068	<.001	5	view →
PAAD	All	All	+0.484	.026	4	view →
ESCA	All	II,III,IV	+0.630	.020	2	view →
CHOL	All	All	+0.401	<.001	2	view →
PRAD	All	All	+0.294	.002	2	view →
ESCA	Female	All	−0.366	.011	1	view →
KIRP	Male	All	−0.251	.039	1	view →
THCA	Female	III,IV	+0.224	.048	1	view →
LUAD	All	All	+0.183	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

TSC22D1-AS1–KIRC

Open the KIRC breakdown →