TRUB2

Across TCGA patient cohorts, TRUB2 mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRUB2-associated genes across cancer lineages are RNU6-567P, THAP12P9, and CTAG1B. Each is linked with TRUB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRUB2-to-partner and partner-to-TRUB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-567P grouped by TRUB2-low versus TRUB2-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRUB2→partner) and Y-score (partner→TRUB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU6-567P →	+0.553	+7.939	<.001	.008	3	3
SKCM	THAP12P9 →	+0.021	+4.867	<.001	.005	3	2
BLCA	CTAG1B →	+0.087	+5.497	<.001	.004	3	2
UCEC	MIR4287 →	+0.300	+4.437	<.001	.005	3	2
UCEC	MIR4514 →	+0.851	+2.902	<.001	.006	3	2
COAD	LINC00265-2P →	+0.078	+5.321	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

RNU6-567P by TRUB2 expression — PRAD

Explore this box plot interactively →