TRUB1

Across TCGA pan-cancer cohorts, TRUB1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TRUB1 data layer compared with 21 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher TRUB1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TRUB1 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

GBM, CCRCC, and LSCC are the cancer types where TRUB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.739	0.407	.004	24	view →
CCRCC	DFS	Tertile	II,III,IV	0.368	0.752	.002	20	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.881	.006	15	view →
HNSC	DFS	Quartile	All	0.546	1.000	.045	8	view →
LUAD	OS	Quartile	All	0.914	0.376	.008	7	view →
PDAC	DFS	Tertile	All	0.455	0.299	.029	3	view →
UCEC	OS	Tertile	All	0.881	1.000	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TRUB1–GBM (OS)

Open the GBM breakdown →