TRPV3

Across TCGA cell cohorts, TRPV3 mutation is significantly associated with the RNA expression of many other genes, with 499 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRPV3-associated genes across cancer lineages are FAM110D, TMEM213, and ZBED3. Each is linked with TRPV3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRPV3-to-partner and partner-to-TRPV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM110D grouped by TRPV3-low versus TRPV3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV3→partner) and Y-score (partner→TRPV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FAM110D →	+0.149	+4.350	<.001	.005	3	2
BLOOD_Leukemia	TMEM213 →	+0.089	+4.491	<.001	<.001	3	2
LARGE_INTESTINE	ZBED3 →	+0.844	+3.321	.001	.003	3	2
SOFT_TISSUE	CYLC1 →	+0.036	+4.930	<.001	.008	3	1
OESOPHAGUS	KRTAP1-4 →	+0.143	+4.906	<.001	.006	3	1
CNS	HELT →	+0.037	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 499 associations by consensus.

FAM110D by TRPV3 expression — BLOOD_Lymphoma

Explore this box plot interactively →