Across TCGA patient cohorts, TRPV1 mutation is significantly associated with the RNA expression of many other genes, with 2,583 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRPV1-associated genes across cancer lineages are ARHGAP19, NEDD8-MDP1, and SENP3-EIF4A1. Each is linked with TRPV1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRPV1-to-partner and partner-to-TRPV1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV1→partner) and Y-score (partner→TRPV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ARHGAP19 →	+0.441	+3.584	.002	.002	3	3
UCEC	NEDD8-MDP1 →	+0.201	+1.518	<.001	.002	3	3
COAD	SENP3-EIF4A1 →	+0.209	+3.529	<.001	.002	3	3
COAD	BAG3 →	+0.650	+3.625	<.001	.001	3	3
UCEC	TBRG1 →	+0.315	+1.691	<.001	<.001	3	3
UCEC	BUB3 →	+0.340	+1.840	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,583 associations by consensus.

Exploration

TRPV1 survival (RNA) · tumor vs normal (RNA) · all TRPV1 data types