TRPS1

Across TCGA cell cohorts, TRPS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,234 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TRPS1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with TRPS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRPS1-to-partner and partner-to-TRPS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TRPS1-low versus TRPS1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPS1→partner) and Y-score (partner→TRPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of myoblast fusion →	+0.081	+0.997	<.001	<.001	3	10
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.080	+1.008	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.103	+1.111	.003	.001	1	12
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.103	+1.158	.002	.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of cytoplasmic translation →	+0.084	+1.683	.002	.004	3	9
STOMACH	Negative regulation of chromosome condensation →	+0.144	+1.737	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,234 associations by consensus.

Negative regulation of myoblast fusion by TRPS1 expression — SKIN

Explore this box plot interactively →