TRPM5

Across TCGA patient cohorts, TRPM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,099 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TRPM5-associated GO terms across cancer lineages are Base-excision repair, Protein methylation, and Obsolete regulation of histone modification. Each is linked with TRPM5 in more than 19 cancer types. Because this analysis shows association rather than direction, both TRPM5-to-partner and partner-to-TRPM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair grouped by TRPM5-low versus TRPM5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPM5→partner) and Y-score (partner→TRPM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Base-excision repair →	+0.040	+0.441	<.001	<.001	3	19
KIRC	Protein methylation →	+0.037	+0.089	<.001	<.001	3	19
MESO	Obsolete regulation of histone modification →	+0.050	+0.122	<.001	.001	3	19
KIRC	Positive regulation of double-strand break repair via homologous recombination →	+0.038	+0.064	<.001	<.001	3	18
KIRC	Depyrimidination →	+0.054	+0.077	<.001	<.001	3	18
STAD	Positive regulation of DNA repair →	+0.033	+0.262	<.001	.009	1	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,099 associations by consensus.

Base-excision repair by TRPM5 expression — STAD

Explore this box plot interactively →