TRPM2-AS

Across TCGA pan-cancer cohorts, TRPM2-AS RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TRPM2-AS’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TRPM2-AS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRPM2-AS is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, BLCA, and STAD are the cancer types where TRPM2-AS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRPM2-AS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+2.106	<.001	10	view →
BLCA	All	III,IV	+1.752	<.001	10	view →
STAD	Male	IV	+3.305	<.001	9	view →
LUSC	Female	All	+1.842	<.001	8	view →
HNSC	Male	IV	+1.755	<.001	8	view →
LUAD	Male	All	+0.761	<.001	7	view →
KIRC	All	All	+0.219	<.001	7	view →
UCEC	All	All	+2.286	<.001	6	view →
BRCA	Female	All	+0.474	.002	6	view →
READ	All	All	+2.282	<.001	5	view →
KICH	All	All	−0.107	.006	4	view →
ESCA	All	II,III,IV	+3.270	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TRPM2-AS–COAD

Open the COAD breakdown →