TRPM1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRPM1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,716 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRPM1-associated genes across cancer lineages are CYTH4, MAN1A1, and ST8SIA4. Each is linked with TRPM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRPM1-to-partner and partner-to-TRPM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPM1 versus CYTH4 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPM1→partner) and Y-score (partner→TRPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCYTH4 →-0.757-0.520<.001<.00132
GBMMAN1A1 →-1.131-0.491<.001<.00132
GBMST8SIA4 →-0.630-0.378<.001.00432
OVEFEMP1 →-1.562-0.634.004.00132
GBMTGFBI →-1.223-0.502<.001<.00132
OVBICC1 →-0.828-0.564.008<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,716 associations by consensus.

TRPM1 vs CYTH4 — GBM

Per-sample scatter of TRPM1 vs CYTH4 in GBM (Pearson r = -0.38).

Explore this scatter interactively →

Exploration