TRPC7-AS2

Across TCGA pan-cancer cohorts, TRPC7-AS2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated TRPC7-AS2 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher TRPC7-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRPC7-AS2 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRC show a favorable association.

UCS, OV, and BRCA are the cancer types where TRPC7-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.102	0.688	<.001	108	view →
OV	OS	Median	All	0.754	0.626	<.001	96	view →
BRCA	OS	Tertile	II,III,IV	0.720	0.917	<.001	72	view →
ACC	OS	Tertile	All	0.113	0.822	<.001	63	view →
COAD	OS	Tertile	IV	0.165	0.596	<.001	60	view →
SKCM	DFS	Tertile	All	0.273	0.617	.004	57	view →
READ	DFS	Tertile	II,III,IV	0.452	0.803	.017	36	view →
KIRC	DFS	Tertile	III,IV	0.761	0.585	.015	24	view →
PAAD	DFS	Tertile	All	0.524	0.229	.009	18	view →
KICH	DFS	Tertile	All	0.531	0.886	.032	9	view →
MESO	DFS	Tertile	IV	0.132	0.405	.041	9	view →
SARC	DFS	Tertile	All	0.251	0.596	.035	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

TRPC7-AS2–UCS (OS)

Open the UCS breakdown →