TRPC7-AS1

Across TCGA pan-cancer cohorts, TRPC7-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TRPC7-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TRPC7-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRPC7-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

KIRC, LUAD, and UVM are the cancer types where TRPC7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.711	0.544	<.001	106	view →
LUAD	DFS	Tertile	II,III,IV	0.503	0.700	.006	47	view →
UVM	DFS	Tertile	All	0.241	0.771	.004	45	view →
ACC	DFS	Tertile	All	0.181	0.677	.002	45	view →
TGCT	DFS	Quartile	II,III,IV	0.518	1.000	.003	32	view →
ESCA	OS	Quartile	All	0.383	0.698	.003	31	view →
BRCA	OS	Quartile	All	0.404	0.622	.001	29	view →
PAAD	DFS	Tertile	All	0.440	0.177	.002	25	view →
KIRP	OS	Quartile	III,IV	0.696	0.391	.018	25	view →
READ	DFS	Tertile	IV	0.884	0.322	.001	24	view →
LGG	DFS	Quartile	All	0.886	0.795	.003	23	view →
DLBC	OS	Tertile	All	0.380	0.875	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TRPC7-AS1–KIRC (OS)

Open the KIRC breakdown →