TRPC7-AS1

Across TCGA pan-cancer cohorts, TRPC7-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TRPC7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TRPC7-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TRPC7-AS1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and READ are the cancer types where TRPC7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRPC7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−1.796	<.001	12	view →
KICH	Male	II,III,IV	−2.003	<.001	8	view →
READ	All	All	−1.388	<.001	7	view →
LIHC	All	All	+0.209	<.001	7	view →
KIRP	All	All	−0.889	.003	6	view →
LUSC	All	All	+0.153	.001	5	view →
LUAD	Female	All	+0.147	.002	5	view →
PAAD	All	All	+0.925	.018	4	view →
BRCA	All	All	+0.124	.001	4	view →
KIRC	All	All	−0.652	.001	3	view →
CHOL	All	All	+0.723	.006	2	view →
PRAD	All	All	+0.658	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TRPC7-AS1–COAD

Open the COAD breakdown →