TRPC3

Across TCGA patient cohorts, TRPC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,517 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRPC3-associated proteins across cancer lineages are PRICKLE2_S806, JCAD_S885, and MYLK. Each is linked with TRPC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRPC3-to-partner and partner-to-TRPC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPC3 versus PRICKLE2_S806 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPC3→partner) and Y-score (partner→TRPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRICKLE2_S806 →	+0.721	+0.261	.002	.001	3	5
BRCA	JCAD_S885 →	+0.603	+0.148	<.001	.001	3	5
OV	MYLK →	+0.766	+0.214	<.001	.007	3	5
BRCA	FKBP7 →	+0.610	+0.156	<.001	<.001	3	5
GBM	GNG2 →	+0.626	+0.424	<.001	.001	3	5
OV	GPX7 →	+0.665	+0.248	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,517 associations by consensus.

TRPC3 vs PRICKLE2_S806 — OV

Explore this scatter interactively →