TRPC3

Across TCGA patient cohorts, TRPC3 protein abundance is significantly associated with the RNA expression of many other genes, with 597 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRPC3-associated genes across cancer lineages are CARD10, ETV7, and RIN3. Each is linked with TRPC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRPC3-to-partner and partner-to-TRPC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPC3 versus CARD10 in LSCC, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPC3→partner) and Y-score (partner→TRPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CARD10 →	+1.228	+1.608	.002	.005	2	1
LSCC	ETV7 →	+1.838	+1.608	.006	.005	2	1
LSCC	RIN3 →	+1.498	+1.608	.003	.005	2	1
LSCC	RP2 →	+0.949	+1.608	.003	.005	2	1
LSCC	STK24 →	+0.836	+1.608	.004	.005	2	1
LSCC	AQP8 →	+0.278	+1.608	.006	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 597 associations by consensus.

TRPC3 vs CARD10 — LSCC

Explore this scatter interactively →