TRMU

Across TCGA cell cohorts, TRMU RNA expression is significantly associated with the go_rna of many other GO terms, with 5,046 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRMU-associated GO terms across cancer lineages are DNA replication, DNA-templated DNA replication, and Meiotic chromosome condensation. Each is linked with TRMU in more than 18 cancer types. Because this analysis shows association rather than direction, both TRMU-to-partner and partner-to-TRMU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by TRMU-low versus TRMU-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMU→partner) and Y-score (partner→TRMU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA replication →	+0.116	+1.017	<.001	<.001	3	19
SOFT_TISSUE	DNA-templated DNA replication →	+0.135	+0.997	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.174	+0.906	<.001	<.001	3	18
BONE	Mitotic chromosome condensation →	+0.139	+0.733	<.001	<.001	3	17
SOFT_TISSUE	Chromosome segregation →	+0.107	+1.044	<.001	<.001	3	16
SOFT_TISSUE	Cell cycle checkpoint signaling →	+0.087	+0.929	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,046 associations by consensus.

DNA replication by TRMU expression — SOFT_TISSUE

Explore this box plot interactively →