TRMT9B

Across TCGA patient cohorts, TRMT9B mutation is significantly associated with the total protein of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT9B-associated genes across cancer lineages are PKC-b-II_pS660, PCNA, and TFRC. Each is linked with TRMT9B in more than 3 cancer types. Because this analysis shows association rather than direction, both TRMT9B-to-partner and partner-to-TRMT9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKC-b-II_pS660 grouped by TRMT9B-low versus TRMT9B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT9B→partner) and Y-score (partner→TRMT9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PKC-b-II_pS660 →	-0.363	-2.115	.002	.017	3	4
COAD	PCNA →	+0.326	+2.713	<.001	.003	3	3
COAD	TFRC →	+0.605	+1.440	<.001	.027	3	3
UCEC	ATM →	-0.646	-1.954	<.001	<.001	3	3
COAD	Caspase-7-cleavedD198 →	+0.976	+2.321	<.001	.005	3	3
UCEC	4E-BP1 →	+0.311	+2.277	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

PKC-b-II_pS660 by TRMT9B expression — COAD

Explore this box plot interactively →