TRMT9B

Across TCGA pan-cancer cohorts, TRMT9B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TRMT9B data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher TRMT9B RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRMT9B expression acts as an unfavorable survival marker, although some lineages such as KIRP and HNSC show a favorable association.

KIRP, HNSC, and COAD are the cancer types where TRMT9B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.977	0.884	<.001	88	view →
HNSC	DFS	Tertile	IV	0.737	0.534	<.001	86	view →
COAD	OS	Quartile	II,III,IV	0.719	0.407	<.001	52	view →
KIRC	DFS	Median	All	0.906	0.836	<.001	46	view →
LGG	OS	Median	All	0.737	0.877	<.001	36	view →
UCEC	DFS	Median	All	0.926	0.867	.006	30	view →
BRCA	OS	Median	All	0.945	0.900	.007	28	view →
STAD	DFS	Median	IV	0.117	0.673	.001	24	view →
READ	OS	Quartile	III,IV	0.753	0.191	.001	21	view →
PAAD	OS	Median	All	0.464	0.306	.015	20	view →
ACC	DFS	Quartile	II,III,IV	0.276	0.606	.008	19	view →
MESO	OS	Median	All	0.196	0.358	.016	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TRMT9B–KIRP (OS)

Open the KIRP breakdown →