TRMT44

Across TCGA pan-cancer cohorts, TRMT44 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRMT44 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TRMT44 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TRMT44 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, UCEC, and LUAD are the cancer types where TRMT44 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.464	0.873	.007	16	view →
UCEC	DFS	Median	All	1.000	0.632	.012	12	view →
LUAD	OS	Median	All	0.323	0.834	.003	12	view →
KIRP	OS	Median	All	0.135	0.703	.002	6	view →
SCLC	DFS	Median	II,III,IV	0.137	0.562	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRMT44–COAD (OS)

Open the COAD breakdown →