TRMT44

Across TCGA cell cohorts, TRMT44 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TRMT44-associated genes across cancer lineages are OPN1MW, S100A12, and CD1B. Each is linked with TRMT44 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT44-to-partner and partner-to-TRMT44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW grouped by TRMT44-low versus TRMT44-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT44→partner) and Y-score (partner→TRMT44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OPN1MW →	+0.016	+4.415	.001	.007	3	1
OVARY	S100A12 →	+0.518	+3.938	.004	.005	3	1
LUNG_SCLC	CD1B →	+0.360	+4.523	<.001	.003	3	1
LUNG_SCLC	LALBA →	+0.077	+4.269	<.001	.005	3	1
LUNG_SCLC	ACER1 →	+0.080	+4.044	<.001	.009	3	1
LUNG_SCLC	OR10K2 →	+0.020	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OPN1MW by TRMT44 expression — SKIN

Explore this box plot interactively →