TRMT2A

Across TCGA patient cohorts, TRMT2A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRMT2A-associated proteins across cancer lineages are RANBP1, PPIL2, and CRKL. Each is linked with TRMT2A in more than 6 cancer types. Because this analysis shows association rather than direction, both TRMT2A-to-partner and partner-to-TRMT2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRMT2A versus RANBP1 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT2A→partner) and Y-score (partner→TRMT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RANBP1 →	+0.573	+0.493	<.001	<.001	3	7
LSCC	PPIL2 →	+0.260	+0.494	<.001	<.001	3	5
OV	CRKL →	+0.325	+0.675	<.001	<.001	3	4
GBM	THOC5 →	+0.348	+0.366	<.001	<.001	3	4
GBM	THOC7 →	+0.298	+0.363	<.001	<.001	3	4
LUAD	PPM1K_S248 →	-0.455	-0.245	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,148 associations by consensus.

TRMT2A vs RANBP1 — LSCC

Explore this scatter interactively →