TRMT2A

Across TCGA cell cohorts, TRMT2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,618 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRMT2A-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and DNA replication proofreading. Each is linked with TRMT2A in more than 17 cancer types. Because this analysis shows association rather than direction, both TRMT2A-to-partner and partner-to-TRMT2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by TRMT2A-low versus TRMT2A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT2A→partner) and Y-score (partner→TRMT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.139	+1.514	<.001	<.001	3	18
URINARY_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.139	+1.514	<.001	<.001	3	18
BONE	DNA replication proofreading →	+0.223	+1.092	.003	<.001	3	15
BONE	Meiotic chromosome condensation →	+0.203	+0.926	.002	<.001	3	11
LUNG_SCLC	DNA topological change →	+0.135	+0.702	.001	.002	2	12
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.074	+0.698	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,618 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by TRMT2A expression — URINARY_TRACT

Explore this box plot interactively →