TRMT11

Across TCGA pan-cancer cohorts, TRMT11 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRMT11 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TRMT11 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRMT11 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

COAD, LSCC, and HNSC are the cancer types where TRMT11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
LSCC	OS	Quartile	All	0.954	0.783	.016	4	view →
HNSC	OS	Tertile	All	0.790	0.937	.019	3	view →
PDAC	DFS	Tertile	II,III,IV	0.288	0.483	.044	2	view →
CCRCC	DFS	Median	II,III,IV	0.806	0.346	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRMT11–COAD (DFS)

Open the COAD breakdown →