TRMT10C

Across TCGA cell cohorts, TRMT10C mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRMT10C-associated genes across cancer lineages are CCDC60, C1orf146, and TMSB4Y. Each is linked with TRMT10C in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT10C-to-partner and partner-to-TRMT10C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC60 grouped by TRMT10C-low versus TRMT10C-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT10C→partner) and Y-score (partner→TRMT10C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CCDC60 →	+0.064	+4.228	<.001	.006	3	1
OVARY	C1orf146 →	+0.040	+4.450	<.001	.004	3	1
LARGE_INTESTINE	TMSB4Y →	+1.668	+3.556	<.001	.007	3	1
LARGE_INTESTINE	OR2V2 →	+0.012	+3.510	.001	.003	3	1
LARGE_INTESTINE	BPY2 →	+0.015	+4.022	<.001	.006	3	1
LARGE_INTESTINE	BPY2B →	+0.015	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

CCDC60 by TRMT10C expression — OVARY

Explore this box plot interactively →