TRMO

Across TCGA cell cohorts, TRMO RNA expression is significantly associated with the go_rna of many other GO terms, with 2,571 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRMO-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Positive regulation of mRNA 3'-end processing, and Immunoglobulin heavy chain V-D-J recombination. Each is linked with TRMO in more than 12 cancer types. Because this analysis shows association rather than direction, both TRMO-to-partner and partner-to-TRMO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by TRMO-low versus TRMO-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMO→partner) and Y-score (partner→TRMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Proteasome regulatory particle assembly →	+0.105	+0.681	.002	.003	2	13
OESOPHAGUS	Positive regulation of mRNA 3'-end processing →	+0.127	+0.822	.003	.001	3	12
SOFT_TISSUE	Immunoglobulin heavy chain V-D-J recombination →	+0.149	+0.495	<.001	<.001	3	12
CNS	Positive regulation of RNA splicing →	+0.102	+0.606	<.001	<.001	3	11
LARGE_INTESTINE	Primary miRNA processing →	+0.092	+0.512	.001	.003	3	10
SOFT_TISSUE	Negative regulation of ubiquitin-protein transferase activity →	+0.140	+0.612	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,571 associations by consensus.

Proteasome regulatory particle assembly by TRMO expression — OESOPHAGUS

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