TRIT1

Across TCGA patient cohorts, TRIT1 mutation is significantly associated with the RNA expression of many other genes, with 933 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIT1-associated genes across cancer lineages are RNU6-642P, SNORA10B, and RN7SKP221. Each is linked with TRIT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIT1-to-partner and partner-to-TRIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-642P grouped by TRIT1-low versus TRIT1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIT1→partner) and Y-score (partner→TRIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-642P →	+0.712	+5.096	<.001	.008	3	2
BRCA	SNORA10B →	+0.410	+5.441	<.001	.005	3	2
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	2
LGG	RNA5SP336 →	+0.340	+5.846	<.001	.003	3	2
LUSC	RPS29P25 →	+0.238	+7.918	<.001	<.001	3	2
CESC	MTND3P9 →	+0.125	+4.969	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 933 associations by consensus.

RNU6-642P by TRIT1 expression — BRCA

Explore this box plot interactively →