TRIR

Across TCGA patient cohorts, TRIR protein abundance is significantly associated with the RNA expression of many other genes, with 13,560 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIR-associated genes across cancer lineages are DDX39A, MMP19, and F13A1. Each is linked with TRIR in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIR-to-partner and partner-to-TRIR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIR versus DDX39A in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIR→partner) and Y-score (partner→TRIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DDX39A →	+0.942	+0.361	<.001	<.001	3	7
GBM	MMP19 →	-1.163	-0.382	<.001	<.001	3	7
GBM	F13A1 →	-1.763	-0.386	.001	.001	3	7
LSCC	HAUS8 →	+0.549	+0.351	<.001	<.001	3	7
UCEC	NR2C2AP →	+0.684	+0.216	<.001	<.001	3	7
HNSC	ZNF443 →	+1.058	+0.338	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,560 associations by consensus.

TRIR vs DDX39A — HNSC

Explore this scatter interactively →