TRIP6

Across TCGA patient cohorts, TRIP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,940 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIP6-associated proteins across cancer lineages are EPHB4, MEPCE, and GTF2I. Each is linked with TRIP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIP6-to-partner and partner-to-TRIP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIP6 versus EPHB4 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP6→partner) and Y-score (partner→TRIP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	EPHB4 →	+0.472	+0.389	<.001	.006	3	6
HNSC	MEPCE →	+0.316	+0.813	<.001	<.001	3	5
HNSC	GTF2I →	+0.460	+0.793	<.001	<.001	3	5
LSCC	TRIP6_S142 →	+0.890	+0.662	.004	.006	3	4
BRCA	TRIP6_S424 →	+0.800	+1.032	.001	.005	3	4
PDAC	ZNF185 →	+0.511	+0.372	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,940 associations by consensus.

TRIP6 vs EPHB4 — PDAC

Explore this scatter interactively →