TRIP6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIP6 protein abundance is significantly associated with the RNA expression of many other genes, with 16,410 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIP6-associated genes across cancer lineages are SYPL1, PLS3, and CAV1. Each is linked with TRIP6 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIP6-to-partner and partner-to-TRIP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIP6 versus SYPL1 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP6→partner) and Y-score (partner→TRIP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSYPL1 →+0.894+0.326.003.00337
GBMPLS3 →+0.927+0.387<.001<.00136
UCECCAV1 →+1.052+0.435<.001<.00136
LUADCRTAP →+0.678+0.423<.001<.00136
HNSCARMC10 →+0.684+0.358.003<.00136
UCECSERTAD4-AS1 →+0.857+0.320.004.00336
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,410 associations by consensus.

TRIP6 vs SYPL1 — HNSC

Per-sample scatter of TRIP6 vs SYPL1 in HNSC (Pearson r = 0.32).

Explore this scatter interactively →

Exploration