TRIP6

Across TCGA cell cohorts, TRIP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,306 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TRIP6-associated GO terms across cancer lineages are Focal adhesion assembly, Positive regulation of substrate adhesion-dependent cell spreading, and Cell-substrate junction assembly. Each is linked with TRIP6 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRIP6-to-partner and partner-to-TRIP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Focal adhesion assembly grouped by TRIP6-low versus TRIP6-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP6→partner) and Y-score (partner→TRIP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Focal adhesion assembly →	+0.117	+2.117	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of substrate adhesion-dependent cell spreading →	+0.110	+1.458	<.001	.004	3	9
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.148	+2.092	<.001	<.001	3	9
PANCREAS	Anterograde neuronal dense core vesicle transport →	+0.164	+2.181	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Cell-substrate junction organization →	+0.134	+1.974	<.001	<.001	3	8
KIDNEY	Pre-mRNA catabolic process →	+0.096	+0.647	.003	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,306 associations by consensus.

Focal adhesion assembly by TRIP6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →