TRIP12

Across TCGA patient cohorts, TRIP12 protein abundance is significantly associated with the RNA expression of many other genes, with 9,552 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TRIP12-associated genes across cancer lineages are ADAM22, UBE2F, and MRPL44. Each is linked with TRIP12 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIP12-to-partner and partner-to-TRIP12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIP12 versus ADAM22 in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP12→partner) and Y-score (partner→TRIP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADAM22 →	-0.910	-0.228	<.001	<.001	3	6
LSCC	UBE2F →	+0.515	+0.280	<.001	<.001	3	6
LSCC	MRPL44 →	+0.480	+0.233	<.001	<.001	3	5
HNSC	AKT3 →	-0.682	-0.161	<.001	.002	3	4
BRCA	FBXL16 →	-1.067	-0.192	.005	.007	3	4
GBM	DLG2 →	-0.593	-0.117	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,552 associations by consensus.

TRIP12 vs ADAM22 — HNSC

Explore this scatter interactively →