TRIP12

Across TCGA cell cohorts, TRIP12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,266 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIP12-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Peptidyl-serine phosphorylation. Each is linked with TRIP12 in more than 15 cancer types. Because this analysis shows association rather than direction, both TRIP12-to-partner and partner-to-TRIP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by TRIP12-low versus TRIP12-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP12→partner) and Y-score (partner→TRIP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal transport →	+0.068	+1.148	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.065	+1.122	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Peptidyl-serine phosphorylation →	+0.074	+1.443	.003	<.001	3	16
LUNG_NSCLC_LUAD	Peptidyl-serine modification →	+0.073	+0.613	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.080	+1.367	<.001	<.001	3	16
SKIN	Retrograde transport, endosome to Golgi →	+0.086	+0.991	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,266 associations by consensus.

Endosomal transport by TRIP12 expression — SKIN

Explore this box plot interactively →