TRIML2

Across TCGA cell cohorts, TRIML2 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible TRIML2-associated genes across cancer lineages are DCSTAMP, KIR3DL3, and MS4A14. Each is linked with TRIML2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIML2-to-partner and partner-to-TRIML2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCSTAMP grouped by TRIML2-low versus TRIML2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIML2→partner) and Y-score (partner→TRIML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DCSTAMP →	+0.239	+4.432	<.001	.003	3	2
LUNG_NSCLC_LUAD	KIR3DL3 →	+0.046	+5.228	<.001	.005	3	2
SOFT_TISSUE	MS4A14 →	+0.081	+4.930	<.001	.008	3	1
LUNG_SCLC	CLDN17 →	+0.174	+4.817	<.001	.001	3	1
LUNG_SCLC	OR2D3 →	+0.048	+4.044	<.001	.009	3	1
LUNG_SCLC	OR56B1 →	+0.063	+4.269	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

DCSTAMP by TRIML2 expression — STOMACH

Explore this box plot interactively →