TRIML2

Across TCGA pan-cancer cohorts, TRIML2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TRIML2 data layer compared with 12 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TRIML2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRIML2 expression acts as an unfavorable survival marker, although some lineages such as DLBC and LIHC show a favorable association.

HNSC, KIRC, and UVM are the cancer types where TRIML2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.690	0.808	<.001	158	view →
KIRC	DFS	Median	All	0.519	0.697	<.001	114	view →
UVM	DFS	Tertile	All	0.249	0.676	<.001	110	view →
BLCA	DFS	Quartile	All	0.397	0.554	<.001	75	view →
LUAD	OS	Quartile	III,IV	0.493	0.750	<.001	57	view →
MESO	OS	Tertile	All	0.181	0.480	<.001	55	view →
KIRP	OS	Quartile	All	0.838	0.963	<.001	53	view →
KICH	DFS	Quartile	All	0.566	0.961	.001	44	view →
THCA	DFS	Tertile	III,IV	0.530	0.835	<.001	41	view →
BRCA	OS	Quartile	III,IV	0.806	0.926	.008	22	view →
THYM	OS	Tertile	IV	0.294	1.000	.025	21	view →
SCLC	DFS	Tertile	II,III,IV	0.292	0.843	.005	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TRIML2–HNSC (OS)

Open the HNSC breakdown →