Across TCGA cell cohorts, TRIML1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible TRIML1-associated genes across cancer lineages are HSFY2, MYH8, and TAAR6. Each is linked with TRIML1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIML1-to-partner and partner-to-TRIML1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIML1→partner) and Y-score (partner→TRIML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	HSFY2 →	+0.049	+4.807	<.001	.006	3	1
PANCREAS	MYH8 →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	TAAR6 →	+0.032	+5.000	<.001	.006	3	1
PANCREAS	MOS →	+0.032	+5.000	<.001	.006	3	1
PANCREAS	RNASE8 →	+0.078	+5.000	<.001	.006	3	1
PANCREAS	CSHL1 →	+0.070	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

TRIML1 survival (RNA) · tumor vs normal (RNA) · all TRIML1 data types