Across TCGA pan-cancer cohorts, TRIML1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated TRIML1 data layer compared with 6 for mutation status.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TRIML1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIML1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LAML show a favorable association.
BLCA, SCLC, and UCS are the cancer types where TRIML1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.