TRIM77

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIM77 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,023 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM77-associated proteins across cancer lineages are WNK2, MYEF2, and PDK3. Each is linked with TRIM77 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM77-to-partner and partner-to-TRIM77 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM77→partner) and Y-score (partner→TRIM77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCWNK2 →+0.667+0.417<.001.00332
LSCCMYEF2 →+0.690+0.401<.001.00132
GBMPDK3 →+0.345+0.037.003<.00132
HNSCBICD2_S582 →-0.395-0.556.008.00932
GBMC2CD5 →+0.325+0.037<.001<.00132
HNSCCLIP1 →-0.317-0.386.002.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,023 associations by consensus.

Exploration