Across TCGA patient cohorts, TRIM77 mutation is significantly associated with the RNA expression of many other genes, with 646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM77-associated genes across cancer lineages are RNA5SP369, RNU6-145P, and RPS27AP14. Each is linked with TRIM77 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM77-to-partner and partner-to-TRIM77 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM77→partner) and Y-score (partner→TRIM77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP369 →	+0.239	+4.539	.006	.008	3	2
READ	RNU6-145P →	+0.352	+4.315	.003	.002	3	2
COAD	RPS27AP14 →	+0.222	+6.003	<.001	.002	3	2
COAD	SNORA10B →	+1.219	+5.693	<.001	.003	3	2
COAD	COX5BP8 →	+0.270	+5.893	<.001	.002	3	2
BRCA	COX5BP1 →	+0.088	+4.797	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 646 associations by consensus.

Exploration

TRIM77 survival (RNA) · tumor vs normal (RNA) · all TRIM77 data types