Across TCGA cell cohorts, TRIM77 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM77-associated genes across cancer lineages are OR5V1, AFM, and OR11H1. Each is linked with TRIM77 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM77-to-partner and partner-to-TRIM77 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM77→partner) and Y-score (partner→TRIM77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR5V1 →	+0.006	+4.022	<.001	.006	3	2
OESOPHAGUS	AFM →	+0.017	+4.392	<.001	.003	3	1
BLOOD_Leukemia	OR11H1 →	+0.080	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.096	+4.705	<.001	.003	3	1
BLOOD_Leukemia	SLC17A4 →	+0.092	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CER1 →	+1.039	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

TRIM77 survival (RNA) · tumor vs normal (RNA) · all TRIM77 data types