TRIM74

Across TCGA patient cohorts, TRIM74 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TRIM74-associated GO terms across cancer lineages are tRNA processing, Protein insertion into mitochondrial inner membrane, and Preassembly of GPI anchor in ER membrane. Each is linked with TRIM74 in more than 23 cancer types. Because this analysis shows association rather than direction, both TRIM74-to-partner and partner-to-TRIM74 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA processing grouped by TRIM74-low versus TRIM74-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM74→partner) and Y-score (partner→TRIM74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA processing →	+0.050	+0.146	<.001	<.001	3	24
KIRC	Protein insertion into mitochondrial inner membrane →	+0.064	+0.304	<.001	<.001	3	24
UVM	Preassembly of GPI anchor in ER membrane →	+0.044	+0.274	<.001	<.001	3	23
STAD	tRNA metabolic process →	+0.048	+0.145	<.001	<.001	2	24
STAD	Macromolecule methylation →	+0.049	+0.162	<.001	<.001	3	23
SCLC	Positive regulation of DNA repair →	+0.062	+0.504	.002	.006	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

tRNA processing by TRIM74 expression — STAD

Explore this box plot interactively →